Leonardo DiCaprio has already been set to star.
WB bought the spec preemptively before other studios got a crack at the material. The subject matter has been kept under tight wraps, with the studio describing the film as a contemporary sci-fi actioner set within the architecture of the mind. Production begins this summer for 2010 release.
Nolan will produce with Emma Thomas.
The film is Nolan's first with Cotillard and Page, but he is reteaming with Murphy, who played the villain Scarecrow in "Batman Begins," with a cameo in "The Dark Knight." Murphy just completed the thriller "Peacock" and "Perrier's Bounty."